the coin known as the Isabella quarter was designed by C.E. Barber.  Therese souvenir quarters were sold for $1.  The obverse has the crowned bust of Queen Isabella of Spain.  The kneeling female on the reverse with distaff and spindle is emblmatic of women's industry.

You could spend $3,000 to $7,000 for a Mint State example, this AU58 in an old green pcgs holder will make someone might happy at a fraction of that!